In the NCRC, clinical studies are carried out in the following groups:
The Cerebrovascular Diseases group, headed by Prof. Dr. Andreas Meisel, focuses on the mechanisms and consequences of stroke-induced immunodepression. The clinical picture of stroke is not only characterized by neurological deficits, but also by the high incidence of infectious complications, in particular, pneumonia. The occurrence of pneumonia in stroke patients is associated with higher mortality and larger neurological deficits. Recent experimental and clinical evidence indicates that stroke-induced immunodepression is an independent risk factor which increases susceptibility to infections. Based on basic research projects by our group at the Center for Stroke Research Berlin (CSB), new diagnostic and therapeutic approaches to stroke treatment have been developed in clinical studies. Growing insight into the mechanisms of immunodepression may enable new immunomodulatory treatment approaches in stroke patients in the future. The improvement of stroke patient care through new care provision structures and care provision research is the main aim of the Berlin Stroke Alliance, a network of Berlin stroke care providers.
Prof. Dr. Andreas Meisel
+49 (0)30 450 660 026
Fax: +49 (0)30 450 539 913
The Cognitive Neurology group under the direction of Prof. Dr. Agnes Flöel focuses on the topics of healthy aging, cognitive impairments in aging, neurorehabilitation following stroke, and vascular and Alzheimer’s dementia. To this end, learning processes in healthy aging or stroke-damaged brain are being investigated (for example, through behavior measurements or MR-based imaging). Building on this, interventional techniques for learning improvement are being developed, especially in the area of language and motor skill recovery following stroke, and in neurodegenerative diseases. This includes learning support through medication, electrical brain stimulation and lifestyle interventions such as physical activity or dietary approaches. In this context, the interaction between response to interventional techniques and genetic disposition is also being investigated.
+49 30 450 660395 (Claudia Schwarz)
General Inquiries concerning Participation in Studies
The Clinical Neuroimmunology group under the direction of Prof. Dr. Friedemann Paul investigates inflammatory and autoimmune diseases of the nervous system such as multiple sclerosis (MS) and neuromyelitis optica (NMO). The team carries out numerous studies to improve diagnosis and treatment of multiple sclerosis and other diseases. The main focus is on developing so-called neuroprotective (nerve cell-protecting) treatment approaches and establishing modern examination procedures such as MRI (magnetic resonance imaging), OCT (optical coherence tomography), and motion analysis.
Prof. Dr. Friedemann Paul
+49 (0)30 450 539 705
Fax: +49 (0) 30 450 539 915
Dr. med. Judith Bellmann-Strobl
+49 (0)30 450 660 162
Fax: +49 (0) 30 450 539 915
The Developmental Disorders of the Nervous System group headed by Prof. Dr. Markus Schülke-Gerstenfeld investigates genetic causes of congenital developmental disorders of the nervous system. These include various forms of epilepsy as well as diseases of the mitochondria (power stations of the cells), the nerves (neuropathies), and the muscles (myopathies). The group’s aim is to uncover new pathomechanisms and to use this knowledge to develop treatment methods. To achieve this, emphasis is placed on close links, cooperation, and efficient channels of communication between patient care, clinical research, and laboratory work.
Prof. Dr. med. Markus Schülke-Gerstenfeld
+49 (0)30 450 566 468
Fax: +49 (0)30 450 539 935