New Junior Groups

As part of our commitment to provide opportunities for early career researchers, NeuroCure will establish several new junior research groups in cooperation with our partner institutions during the current funding period. 

New groups established so far include:

Hanna Hörnberg

 Hanna Hörnberg

Affiliation

Max Delbrück Center for Molecular Medicine (MDC)

Research Focus

The Molecular and Cellular Basis of Behavior group is focused on understanding how genetic and environmental factors shape the molecular composition of neural circuits. We are particularly interested in the neural circuits associated with social and emotional behaviors. To study this, we combine behavioral neuroscience in mouse models with cell- and circuit-specific tools to investigate the molecular mechanisms influencing these behaviors. Our focus is to explore how these mechanisms are affected by social experiences and genetic background associated with neuropsychiatric and neurodevelopmental conditions.

Rachel Lippert

Dr.

Dr. Rachel Lippert

Affiliation

German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE)

Research Focus

The Neurocircuit Development and Function (NDF) group is engaged in understanding how neural circuits involved in the control of energy homeostasis develop and function within complex networks in the brain. Specifically, the team wants to understand how maternal nutrition and altered maternal metabolism can negatively impact the proper formation and function of these brain circuits, resulting in the potential for an earlier onset of brain-related diseases. This work is performed using rodent model systems to target the function of specific neuronal systems to better understand their role in metabolism and behavior.

Noa Lipstein

Dr.

Dr. Noa Lipstein

Affiliation

Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP)

Research Focus

The Synapse Biology group focuses on elucidating the contribution of synaptic proteins to neuronal function and plasticity, and on deciphering synaptic disease mechanisms in brain disorders. We combine genetic manipulations in mouse models with electrophysiological and cell-type-specific biochemical tools to study the molecular composition and organization of synapses, with the aim of understanding how these define synaptic function and dysfunction.

Christian Meisel

PD Dr. med.

PD Dr. med. Christian Meisel

Affiliation

Berlin Institute of Health (BIH)

Research Focus

The Computational Neurology group develops theory- and data-driven methods to better monitor, predict and prevent health deteriorations in epilepsy, intensive care and other neurology settings. Our approach utilizes multimodal time series data over the health-disease continuum, including wearables, in-hospital neuromonitoring, video and EEG. We are exploring the relevance of dynamical systems frameworks for system function in neurology, among them the critical brain hypothesis. Our work is motivated by a more quantitative, data-driven understanding of health and disease that will ultimately afford more proactive treatment options.

Marina Mikhaylova

Prof. Dr.

Prof. Dr. Marina Mikhaylova

Affiliation

Humboldt-Universität zu Berlin (HU)

Research Focus

The Optobiology group combines biochemical, biophysical, molecular biological and bioinformatic methods with advanced imaging techniques to tackle questions dealing with different aspects of neuronal cell biology. Current projects explore roles of the microtubule and actin cytoskeleton as well as intracellular organelle trafficking in controlling the formation, stability and plasticity of synaptic contacts in health and disease.

Silvia Viana da Silva

Dr.

Dr. Silvia Viana da Silva

Affiliation

German Center for Neurodegenerative Diseases (DZNE)

Research Focus

The Cellular Circuits of Memory group is focused on understanding how neuronal circuits in the hippocampal-associated brain regions are altered in normal aging as well as in memory pathologies. We use electrophysiological methods to investigate brain oscillations and single cell activity in animals while they perform different behavioral tasks. Taking advantage of transgenic mouse lines and genetic manipulations with viral vectors we try to understand how different cell types are involved in the formation of short and long-lasting memories. Our work is aimed at identifying altered neuronal circuits with the potential for manipulation in order to ameliorate or restore memory impairments in neurodegenerative diseases such as Alzheimer’s disease.